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Os tumores seminomatosos são os tumores de células germinativas compostos por células que se assemelham às células germinativas primordiais ou gonócitos iniciais, enquanto os tumores não-seminomatosos são as massas que contêm células-tronco embrionárias indiferenciadas que podem se diferenciar entre diferentes linhagens celulares. O seminoma de mediastino possui curso clínico relativamente favorável, sendo o prognóstico melhor que do tumor mediastinal não-seminomatoso e pior que do seminoma gonadal primário. Isso ocorre porque a túnica albugínea do testículo confina o tumor e previne a disseminação local por longo período, ao passo que, no mediastino, pela proximidade dos grandes vasos, a disseminação Resumen - Seminoma vs no seminoma Los tumores seminomatosos son los tumores de células germinales compuestos de células que se asemejan a las células germinales primordiales o gonocitos tempranos, mientras que los tumores no seminomatosos son las masas que contienen células madre embrionarias indiferenciadas que pueden diferenciarse entre diferentes líneas celulares. In patients with metastatic disease treated with three or more cycles of cisplatin- based chemotherapy, TIN in the contralateral non-resected testicle may be A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other Tumors with both seminoma and nonseminoma elements or that occur with the presence of AFP should be treated as nonseminomas. Abdominal CT or &nb The germinomatous or seminomatous germ-cell tumors (GGCT, SGCT) include only germinoma and its synonyms dysgerminoma and seminoma.

5 Aug 2020 Non-seminomas depicted more frequently vascular invasion (p = 0.002), but there were no significant differences in tumor size or proportion of Find out information about testicular cancer, including incidence and mortality, screening, symptoms and diagnosis, There are two main types, seminoma and non-seminoma. pain or ache in the lower abdomen, the testicle or scrotum. Nonseminomatous germ cell cancer occurs in slightly younger patients than in I non-seminomatous germ cell testicular cancer (NSGCT I) with or without risk Nonseminoma tumors are more likely than the seminoma type to metastasize, or spread, beyond the testicle. About half of all germ cell tumors are seminomas. two main types of testicular germ cell cancer, seminomas and non-seminomas. They can be made of just one cell type, or they may be made of a mixture. 11 Sep 2019 Risk stratification (good, intermediate, or poor risk).

A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, Non-Seminoma: Stage II Overview. Patients with stage II non-seminoma have cancer that involves the testicle and the retroperitoneal lymph nodes and is curable in over 90% of cases.

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2 and low gestational age being associated with increased risk of non-seminomas, but not of mixed S/NS TGCC, and low maternal age being associated with increased risk of mixed S/NS TGCC, but not of non-seminomatous TGCC. This update refers to the Testicular seminoma and non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

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DOI: to any names, marks, products, or services of third parties or hypertext links to third-. For patients who are unwilling or unable to undergo surveillance, chemotherapy and surgery are alternate options. For more information about testicular cancer, The 5-year cause-specific survival for patients with stage I seminoma or NSGCT is surveillance for nonseminoma [18], which is also based on the presence or In most cancers, the abnormal cells grow to form a lump or mass called a tumor. Many testicular cancers have both seminoma and nonseminoma cells.

Seminomas can also respond well to chemotherapy. However, if you have a mixture of the two types, including seminoma and some nonseminoma, then we treat that as what's called a "mixed germ cell tumor" and it would be treated more as a nonseminomatous germ cell tumor that does not respond well to radiation. Testicular seminoma is the most common malignant tumor of the testis.
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Testicular seminoma originates in the germinal epithelium of the seminiferous tubules.

For non-seminoma, AFP and hCG should be measured every one to two months in the first year after treatment ends, every two to four months in the second year, every three to six months in the third and fourth years, every six months in the fifth year, and annually thereafter, continuing for at least 10 years.
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Both seminoma and NSGCT occur at about the same rate, and men can have seminoma, NSGCT or a combination of both.

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A variety of factors ultimately influence a patient’s decision to receive treatment of cancer. 2008-11-07 · A recent report noted that 21% of seminoma patients on surveillance were lost to follow-up after a median of 5.5 years. At least 5% of relapses occur after five years, suggesting that non-compliant patients will present with more advanced disease, need more intensive treatment, and experience worse overall outcomes. No UK-wide survival statistics are available for testicular cancer that has spread. The survival statistics below are from a large international study. Pure seminoma.

Embryonal carcinoma.